⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805574 | 0.91 | CYP2C19 (0.37) | — | |
| SCHEMBL11805596 | 0.89 | CYP2C19 (0.36) | — | |
| SCHEMBL2112190 | 0.80 | CYP2C19 (0.42) | — | |
| SCHEMBL8340216 | 0.80 | — | — | |
| SCHEMBL426229 | 0.78 | — | — | |
| SCHEMBL8963639 | 0.75 | — | — | |
| SCHEMBL7088538 | 0.75 | — | — | |
| SCHEMBL14041166 | 0.75 | — | — | |
| SCHEMBL9197945 | 0.75 | — | — | |
| SCHEMBL1275144 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109762117-A | The synthetic method of polyether polyol | 山东蓝星东大有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-109762117-A | The synthetic method of polyether polyol | 山东蓝星东大有限公司 | 2019-05-17 | — | — | CN | disclosed |
| US-9598466-B2 | Glycopeptide constructs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-03-21 | — | — | US | disclosed |
| US-20120039843-A1 | CONJUGATES OF A POLYPEPTIDE AND AN OLIGOSACCHARIDE | N.V. ORGANON (NL) | 2012-02-16 | — | — | US | disclosed |
| US-8106007-B2 | Having affinity to antithrombin III; improved pharmacokinetic properties when compared to the original polypeptides | N.V. ORGANON (NL) | 2012-01-31 | — | — | US | disclosed |
| US-20110229510-A1 | GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-09-22 | — | — | US | disclosed |
| US-7910088-B2 | Multivalent constructs for therapeutic and diagnostic applications | BRACCO SUISSE SA (CH) | 2011-03-22 | — | — | US | disclosed |
| US-7807136-B2 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | Rose, David S. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20100062006-A9 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | MAYERS GEORGE L | 2010-03-11 | — | — | US | disclosed |
| US-7459429-B2 | Method of treating disturbances of iron distribution in inflammatory intestinal diseases | HOFFMANN-LA ROCHE INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20080139459-A1 | Conjugates A Polypeptide And A Pentasaccharide | N.V. ORGANON (NL) | 2008-06-12 | — | — | US | disclosed |
| US-20070106064-A1 | Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same | DEVELOPMENT CENTER FOR BIOTECHNOLOGY | 2007-05-10 | — | — | US | disclosed |
| US-20070106064-A1 | Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same | DEVELOPMENT CENTER FOR BIOTECHNOLOGY | 2007-05-10 | — | — | US | disclosed |
| CN-1073451-A | Latent thiol amine-thiol chain transfer agents and the application in polymkeric substance is synthetic thereof | ROHM & HAAS (US) | 1993-06-23 | — | — | CN | disclosed |
| US-4473391-A | Herbicides containing thiazolo[2,3-b]quinazolones as active ingredients, and their use for regulating plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |
| US-4338435-A | Benzothiadiazines having diuretic activity | E. R. SQUIBB & SONS, INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4052545-A | PROCESS FOR POLYMERIZING CONJUGATED DIENES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1977-10-04 | — | — | US | disclosed |
| US-3948869-A | Process for polymerizing conjugated dienes | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-04-06 | — | — | US | disclosed |