Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13125841 | 0.86 | APP (0.45) | PDK2APPMAPT | |
| SCHEMBL15591029 | 0.86 | PDK2 (0.43) | PDK2KCNH2PGRLPLLIPG | |
| SCHEMBL14382063 | 0.86 | PDK2 (0.41) | PDK2APPKCNH2PGRLPL | |
| SCHEMBL15614292 | 0.85 | PDK2 (0.41) | PDK2KCNH2PGRLPLLIPG | |
| SCHEMBL10109288 | 0.85 | APP (0.48) | PDK2APPMAPTKDM4E | |
| SCHEMBL13020759 | 0.85 | APP (0.48) | PDK2APPMAPTKDM4E | |
| SCHEMBL6365284 | 0.84 | PDK2 (0.48) | PDK2KCNH2PGRLPLLIPG | |
| SCHEMBL13125862 | 0.84 | APP (0.47) | PDK2APPMAPTKDM4E | |
| SCHEMBL15070069 | 0.83 | PDK2 (0.48) | PDK2KCNH2PGRLPLLIPG | |
| SCHEMBL13020737 | 0.83 | APP (0.43) | PDK2APPPGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552419-B2 | Cross-conjugated polymers for organic electronic devices and related methods | UNIVERSITY OF WASHINGTON (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120112170-A1 | CROSS-CONJUGATED POLYMERS FOR ORGANIC ELECTRONIC DEVICES AND RELATED METHODS | UNIVERSITY OF WASHINGTON (US) | 2012-05-10 | — | — | US | disclosed |