Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12254135 | 0.94 | FLT3 (0.35) | FLT3TYRO3MERTKGAS6DGAT1 | |
| SCHEMBL10014998 | 0.91 | ESR2 (0.34) | — | |
| SCHEMBL10015006 | 0.90 | FLT3 (0.33) | FLT3TYRO3MERTKGAS6DGAT1 | |
| SCHEMBL12254134 | 0.90 | FLT3 (0.34) | FLT3TYRO3MERTKGAS6 | |
| SCHEMBL12254140 | 0.85 | FLT3 (0.35) | FLT3TYRO3MERTKGAS6 | |
| SCHEMBL17365828 | 0.83 | ESR2 (0.31) | — | |
| SCHEMBL12254133 | 0.83 | FLT3 (0.32) | FLT3TYRO3MERTKGAS6 | |
| SCHEMBL19829132 | 0.82 | NPC1 (0.32) | — | |
| SCHEMBL12254191 | 0.79 | — | — | |
| SCHEMBL19829669 | 0.79 | ESR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137154-B1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| US-8163200-B2 | Cyclohexene compounds for liquid-crystalline mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-24 | — | — | US | disclosed |
| US-8163200-B2 | Cyclohexene compounds for liquid-crystalline mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-24 | — | — | US | disclosed |
| US-8012547-B2 | Pyridine compounds for liquid-crystalline mixtures | MERCH PATENT GMBH (DE) | 2011-09-06 | — | — | US | disclosed |
| US-8012547-B2 | Pyridine compounds for liquid-crystalline mixtures | MERCH PATENT GMBH (DE) | 2011-09-06 | — | — | US | disclosed |
| EP-2052055-B1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2011-07-06 | — | — | EP | disclosed |
| US-20100237285-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100237285-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100127212-A1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-20100127212-A1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-27 | — | — | US | disclosed |
| WO-2008128622-A2 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008019743-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100237285-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | C1S, CHRM1, C1R | FLT3 4577/4885TYRO3 4759/4885MERTK 4762/4885 |
| US-20100127212-A1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | CHRM1, CHRM2, CHRM4 | FLT3 2683/4885TYRO3 3856/4885MERTK 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.