SCHEMBL10015474

SCHEMBL10015474

CCC(O)CC(C)OCC(O)CS

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015463 0.87 TDP1 (0.38) TDP1
SCHEMBL20117658 0.82 TDP1 (0.34) TDP1
SCHEMBL10015473 0.80 TDP1 (0.33) TDP1
SCHEMBL12517107 0.73 TDP1 (0.40) TDP1
SCHEMBL2353818 0.73 TDP1 (0.40) TDP1
SCHEMBL6745509 0.73
SCHEMBL18327202 0.72 TDP1 (0.50) TDP1
SCHEMBL14671018 0.72 KDM4E (0.43) TDP1LMNA
SCHEMBL1829740 0.71 TDP1 (0.41) TDP1LMNA
SCHEMBL5851531 0.71 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8728326-B2 Polymer and methods for preparing and using the same GENERAL ELECTRIC COMPANY (US) 2014-05-20 US disclosed
US-20120152851-A1 POLYMER AND METHODS FOR PREPARING AND USING THE SAME BL TECHNOLOGIES, INC. 2012-06-21 US disclosed