⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14317920 | 1.00 | — | — | |
| SCHEMBL408049 | 1.00 | — | — | |
| Ethane SCHEMBL27729336 | 0.98 | CYP17A1 (0.44) | — | |
| Iodide SCHEMBL20816028 | 0.98 | CYP17A1 (0.44) | — | |
| Bromide SCHEMBL25395862 | 0.98 | CYP17A1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL25396071 | 0.98 | CYP17A1 (0.44) | — | |
| Water SCHEMBL28822856 | 0.98 | CYP17A1 (0.44) | — | |
| Methane SCHEMBL27640067 | 0.98 | CYP17A1 (0.44) | — | |
| Butane SCHEMBL27786045 | 0.96 | CYP17A1 (0.42) | — | |
| SCHEMBL29007526 | 0.94 | CYP17A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170027871-A1 | PHARMACEUTICAL COMBINATION FORMULATION COMPRISING AMLODIPINE, LOSARTAN AND ROSUVASTATIN | HANMI PHARM. CO., LTD. (KR) | 2017-02-02 | — | — | US | disclosed |
| US-20160333413-A1 | BREAST CANCER PROGNOSTICATION AND SCREENING KITS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME (US) | 2016-11-17 | — | — | US | disclosed |
| US-9291909-B2 | Composition comprising a polymeric thermal acid generator and processes thereof | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) | 2016-03-22 | — | — | US | disclosed |
| US-20140342290-A1 | COMPOSITION COMPRISING A POLYMERIC THERMAL ACID GENERATOR AND PROCESSES THEREOF | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) | 2014-11-20 | — | — | US | disclosed |
| EP-2420839-A2 | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2012-02-22 | — | — | EP | disclosed |
| US-20100183851-A1 | Photoresist Image-forming Process Using Double Patterning | CAO YI | 2010-07-22 | — | — | US | disclosed |
| US-7745077-B2 | Composition for coating over a photoresist pattern | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20090317739-A1 | Composition for Coating over a Photoresist Pattern | MERCK PATENT GMBH (DE) | 2009-12-24 | — | — | US | disclosed |