SCHEMBL10016786

SCHEMBL10016786

CCc1ccc2cc(-c3c4ccccc4c(-c4ccc(-c5ccc(-c6ccncc6)cc5)c5ccccc45)c4ccccc34)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP2A6 P11509 1/20 0.43
MAPT P10636 3/20 0.39
CYP17A1 P05093 2/20 0.39
MAPK9 P45984 3/20 0.38
MAPK10 P53779 3/20 0.38
MAPK8 P45983 2/20 0.38
MAPK14 Q16539 5/20 0.38
CSNK1D P48730 4/20 0.38
MAPK11 Q15759 4/20 0.38
CYP3A4 P08684 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
GCGR P47871 1/20 0.37
PIK3CA P42336 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017121 0.99 CYP1A2 (0.44) CYP1A2CYP2A6MAPTCYP17A1MAPK9
SCHEMBL10017236 0.96 CYP1A2 (0.42) CYP1A2CYP2A6MAPTCYP17A1MAPK9
SCHEMBL10016787 0.90 MAPT (0.40) CYP1A2CYP2A6MAPTCYP17A1MAPK9
SCHEMBL10017123 0.89 CYP1A2 (0.38) CYP1A2CYP2A6MAPTCYP17A1MAPK9
SCHEMBL10016782 0.88 MAPT (0.48) CYP1A2CYP2A6MAPTCYP17A1CYP3A4
SCHEMBL10017079 0.88 CYP11B1 (0.38) CYP1A2CYP2A6MAPTMAPK9MAPK10
SCHEMBL10017083 0.88 MAPT (0.37) CYP1A2CYP2A6MAPTCYP17A1MAPK9
SCHEMBL10032721 0.85 CYP17A1 (0.46) CYP1A2CYP2A6MAPTCYP17A1MAPK9
SCHEMBL10017119 0.85 MAPT (0.49) CYP1A2CYP2A6MAPTCYP17A1CYP3A4
SCHEMBL10017099 0.85 MAPK9 (0.38) CYP1A2CYP2A6MAPTMAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012005214-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME JNC株式会社 (JP) 2012-01-12 WO disclosed