SCHEMBL10016882

SCHEMBL10016882

CCc1ccc2cc(-c3c4ccccc4c(-c4ccc(-c5cccnc5-c5ccccc5)c5ccccc45)c4ccccc34)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
MAPT P10636 3/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
FEN1 P39748 1/20 0.36
LMNA P02545 2/20 0.34
HPGD P15428 1/20 0.34
SUCNR1 Q9BXA5 1/20 0.34
DHODH Q02127 3/20 0.33
MAPKAPK2 P49137 1/20 0.33
RIOK2 Q9BVS4 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017099 0.94 MAPK9 (0.38) CYP1A2CYP2A6MAPTLMNADHODH
SCHEMBL10016888 0.91 CYP1A2 (0.38) CYP1A2CYP2A6MAPTPTGS1PTGS2
SCHEMBL10016928 0.89 MAPT (0.44) CYP1A2CYP2A6MAPTPTGS2CYP19A1
SCHEMBL10017162 0.89 MCL1 (0.40) CYP1A2CYP2A6MAPTLMNAHPGD
SCHEMBL10017085 0.82 CYP1A2 (0.31) CYP1A2CYP2A6
SCHEMBL10017104 0.81 CYP1A2 (0.42) CYP1A2CYP2A6MAPTLMNAHPGD
SCHEMBL10017119 0.81 MAPT (0.49) CYP1A2CYP2A6MAPTCYP19A1CYP11B1
SCHEMBL10016891 0.80 MAPKAPK2 (0.39) CYP1A2CYP2A6MAPTLMNAHPGD
SCHEMBL10016893 0.80 CYP1A2 (0.38) CYP1A2CYP2A6MAPTLMNAHPGD
SCHEMBL10016886 0.80 MAPT (0.42) CYP1A2CYP2A6MAPTDHODHCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012005214-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME JNC株式会社 (JP) 2012-01-12 WO disclosed