SCHEMBL10017366

SCHEMBL10017366

CCCCC/C=C\C/C=C\CCCCCCCCOP(O)(O)=S

nearest known ligand 0.90

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 11/20 0.90
LPAR2 Q9HBW0 8/20 0.90
LPAR1 Q92633 5/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017367 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL3832990 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL192973 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL10017369 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL14515933 0.91 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL10017372 0.91 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL192857 0.91 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL8468251 0.84 LPAR3 (0.80) LPAR3LPAR2LPAR1
SCHEMBL31060667 0.84 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL193156 0.84 LPAR3 (1.00) LPAR3LPAR2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120010424-A1 LPA Receptor Agonists and Antagonists RXBIO INC. 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010424-A1 LPA Receptor Agonists and Antagonists LPAR1, LPAR2, LPAR4 LPAR3 4/4885LPAR2 2/4885LPAR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.