SCHEMBL10017833

SCHEMBL10017833

C[C@H]1CC[C@H](C2CCC(c3cc(F)c(OC=C(F)F)c(F)c3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13112193 1.00 ESR2 (0.35) ESR2
SCHEMBL13112195 0.88 ESR2 (0.33) ESR2
SCHEMBL13198630 0.84
SCHEMBL13112194 0.84 ESR2 (0.40) ESR2
SCHEMBL13198623 0.83 CYP2C9 (0.38)
SCHEMBL11957395 0.83 FASN (0.39) ESR2
SCHEMBL2741557 0.83 ESR2 (0.42) ESR2
SCHEMBL15460679 0.82
SCHEMBL8731332 0.81
SCHEMBL13198624 0.81 CYP2C9 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9212244-B2 Polymers made from mixtures comprising vinyl ether monomers MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2015-12-15 US disclosed
US-9212244-B2 Polymers made from mixtures comprising vinyl ether monomers MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2015-12-15 US disclosed
US-20120009393-A1 POLYMERS MADE FROM MIXTURES COMPRISING VINYL ETHER MONOMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-01-12 US disclosed