SCHEMBL10020922

SCHEMBL10020922

CCC(CC)c1ccc(-c2c3ccc(=[N+](CCOCCOC)CCOCCOC)cc-3oc3cc(N(CC)CCc4ccc([N+](=O)[O-])cc4)ccc23)c(O)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ PPARG P37231 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41
▸ NCOR2 Q9Y618 1/20 0.41
▸ FPR2 P25090 4/20 0.34
▸ AVPR2 P30518 2/20 0.32
▸ SLC6A4 P31645 2/20 0.31
▸ CHRM1 P11229 2/20 0.31
▸ P2RY6 Q15077 1/20 0.31
▸ CDC25C P30307 1/20 0.31
▸ TGM2 P21980 1/20 0.31
▸ KCNH2 Q12809 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020919 0.97 MEN1 (0.40) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020914 0.91 MEN1 (0.42) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020916 0.91 MEN1 (0.42) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10052147 0.88 MEN1 (0.37) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020926 0.83 MEN1 (0.40) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020924 0.83 MEN1 (0.40) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020920 0.82 MEN1 (0.51) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020929 0.81 MEN1 (0.52) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020931 0.80 MEN1 (0.48) MEN1KMT2AUSP2POLBPPARG
SCHEMBL10020921 0.78 MEN1 (0.43) MEN1KMT2AUSP2POLBPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101655-B2 Fluorescent dyes and complexes SMITH GERALD ARTHUR (GB) 2012-01-24 — — US disclosed
US-8101655-B2 Fluorescent dyes and complexes SMITH GERALD ARTHUR (GB) 2012-01-24 — — US disclosed
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-10-07 — — US disclosed
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-10-07 — — US disclosed
US-7674918-B2 Fluorescent dyes and complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-03-09 — — US disclosed
US-7674918-B2 Fluorescent dyes and complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-03-09 — — US disclosed
US-20070238884-A1 Fluorescent Dyes and Complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-11 — — US disclosed
US-20070238884-A1 Fluorescent Dyes and Complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238884-A1 Fluorescent Dyes and Complexes F12, PYM1, ANXA6 MEN1 3023/4885KMT2A 4230/4885USP2 4580/4885
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES F12, ANXA6, PYM1 MEN1 2188/4885KMT2A 4351/4885USP2 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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