SCHEMBL10021891

SCHEMBL10021891

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO[C@@H]1OC(CO)[C@@H](O[C@@H]2OC(CO)[C@H](O)[C@H](O[C@]3(OC=O)C[C@@H](O)[C@@H](C)C([C@H](O)[C@@H](CO)O[C@]4(OC=O)C[C@@H](O)[C@@H](C)C([C@H](O)[C@H](O)CO)O4)O3)C2O)[C@H](O)C1O)NC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SELP P16109 11/20 0.53
▸ SIGLEC7 Q9Y286 5/20 0.42
▸ APP P05067 1/20 0.41
▸ SELL P14151 1/20 0.38
▸ CETP P11597 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17789070 0.97 SELP (0.51) SELPSIGLEC7APPSELLCETP
SCHEMBL17789072 0.97 SELP (0.51) SELPSIGLEC7APPSELLCETP
SCHEMBL17789069 0.97 SELP (0.51) SELPSIGLEC7APPSELLCETP
SCHEMBL10021893 0.97 SELP (0.57) SELPSIGLEC7APPSELLCETP
SCHEMBL10021896 0.96 SELP (0.51) SELPSIGLEC7APPSELLCETP
SCHEMBL17789071 0.94 SELP (0.54) SELPSIGLEC7APPSELLCETP
SCHEMBL10021892 0.93 SELP (0.61) SELPAPPCETP
SCHEMBL10021888 0.93 SELP (0.53) SELPSIGLEC7APPSELLCETP
SCHEMBL10021889 0.93 SELP (0.55) SELPSIGLEC7APPSELLCETP
SCHEMBL10021894 0.92 SELP (0.53) SELPSIGLEC7APPSELLCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160151401-A1 GLYCOLIPIDS AS TREATMENT FOR DISEASE LA JOLLA PHARMACEUTICAL COMPANY 2016-06-02 — — US disclosed
US-20120035120-A1 GLYCOLIPIDS AS TREATMENT FOR DISEASE SENEB BIOSCIENCES, INC. (US) 2012-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035120-A1 GLYCOLIPIDS AS TREATMENT FOR DISEASE GBA2, UGCG, GBA1 SELP 2417/4885SIGLEC7 696/4885APP 720/4885
US-20160151401-A1 GLYCOLIPIDS AS TREATMENT FOR DISEASE GBA2, UGCG, GBA1 SELP 2417/4885SIGLEC7 696/4885APP 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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