SCHEMBL10022050

SCHEMBL10022050

C=CC1C=CC(c2ccc(OCc3ccc(C4CO4)c(F)c3)cc2)CC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
OPRM1 P35372 2/20 0.32
OPRD1 P41143 2/20 0.32
MAOB P27338 6/20 0.32
MRGPRX4 Q96LA9 1/20 0.32
MAOA P21397 2/20 0.32
KCNH2 Q12809 3/20 0.32
HTR6 P50406 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
SCN3A Q9NY46 2/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15221042 0.81 PPARD (0.43) MAOBMAOAPPARGPPARDPPARA
SCHEMBL12823804 0.71 BRD4 (0.35) BRD4MAOBMAOAPPARGPPARD
SCHEMBL10022133 0.71
SCHEMBL12823839 0.71 NR1H4 (0.35) BRD4
SCHEMBL12822614 0.66 MAOB (0.39) BRD4MAOBMAOA
SCHEMBL18430827 0.66 BRD4 (0.39) BRD4HTR6
SCHEMBL12823001 0.65 F10 (0.35) BRD4MAOBMAOA
SCHEMBL13586502 0.65 F10 (0.36) BRD4MAOBMAOA
SCHEMBL12823837 0.64 FFAR4 (0.35) BRD4MAOBMAOAHTR6
SCHEMBL10022051 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012053421-A1 CYCLOHEXENE-3,6-DIYL COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC株式会社 (JP) 2012-04-26 WO disclosed