Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAPDH | P04406 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386524 | 0.97 | NPC1 (0.48) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18869474 | 0.91 | NPC1 (0.48) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12386525 | 0.91 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL2303014 | 0.90 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18522409 | 0.90 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21142059 | 0.89 | NPC1 (0.48) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL23366546 | 0.88 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18808120 | 0.88 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21884777 | 0.87 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL22071979 | 0.87 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556382-B2 | Polymerisable mixtures and the use thereof in liquid crystal displays | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9556382-B2 | Polymerisable mixtures and the use thereof in liquid crystal displays | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| EP-2596034-B1 | POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |
| EP-2340292-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130114010-A1 | POLYMERISABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130114010-A1 | POLYMERISABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012022391-A2 | POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |
| US-20110205482-A1 | LIQUID-CRYSTAL DISPLAY | MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) | 2011-08-25 | — | — | US | disclosed |
| US-20110205482-A1 | LIQUID-CRYSTAL DISPLAY | MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) | 2011-08-25 | — | — | US | disclosed |
| WO-2010049044-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2010-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110205482-A1 | LIQUID-CRYSTAL DISPLAY | VCL, LPXN, LCP1 | NPC1 4181/4885RAB9A 2121/4885MEN1 2820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.