Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 7/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908141 | 0.89 | PDE2A (0.50) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL6722530 | 0.89 | PDE2A (0.50) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL6722527 | 0.89 | PDE2A (0.50) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL720256 | 0.89 | PDE2A (0.50) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL369266 | 0.89 | PDE2A (0.50) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL10024087 | 0.87 | PDE2A (0.45) | ADKPRMT5METTL3PDE2AADORA3 | |
| SCHEMBL10024086 | 0.87 | ALB (0.46) | ADKPRMT5PDE2AADORA3ADORA2A | |
| SCHEMBL10024109 | 0.87 | PDE2A (0.45) | ADKPRMT5METTL3PDE2AADORA3 | |
| SCHEMBL10024073 | 0.87 | PDE2A (0.40) | ADKPRMT5METTL3PDE2AADORA3 | |
| SCHEMBL10885781 | 0.79 | PDE2A (0.49) | PDE2AADORA3ADORA2AADORA1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101740-B2 | Positron emission tomography probes for imaging immune activation and selected cancers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-24 | — | — | US | disclosed |
| US-20090105184-A1 | POSITRON EMISSION TOMOGRAPHY PROBES FOR IMAGING IMMUNE ACTIVATION AND SELECTED CANCERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105184-A1 | POSITRON EMISSION TOMOGRAPHY PROBES FOR IMAGING IMMUNE ACTIVATION AND SELECTED CANCERS | PAICS, ADA, DCTD | ADK 137/4885PRMT5 2659/4885METTL3 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.