Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026433 | 1.00 | PTPN1 (0.43) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL13966821 | 0.97 | PTPN1 (0.46) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL12056708 | 0.95 | PTPN1 (0.43) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL13990345 | 0.95 | PTPN1 (0.49) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL13038510 | 0.93 | ADORA1 (0.46) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL13223430 | 0.93 | PTPN1 (0.49) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL14507752 | 0.93 | PTPN1 (0.46) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL13223420 | 0.92 | PTPN1 (0.52) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL31674617 | 0.91 | PTPN1 (0.50) | PTPN1OPRM1OPRK1ADORA1ADORA3 | |
| SCHEMBL13498726 | 0.91 | PTPN1 (0.50) | PTPN1OPRM1OPRK1ADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148539-B2 | Cyanine dye labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | WEST RICHARD M | 2010-10-21 | — | — | US | disclosed |
| US-7750163-B2 | Cyanine dye labelling reagents | GE Healthcare U.K. Limited (GB) | 2010-07-06 | — | — | US | disclosed |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | GE HEALTHCARE UK LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | IK, H1-5, H1-3 | PTPN1 3323/4885OPRM1 4121/4885OPRK1 3216/4885 |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | IK, H1-5, H1-3 | PTPN1 3312/4885OPRM1 4270/4885OPRK1 3564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.