Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065025 | 0.86 | CYP3A4 (0.44) | DRD2CYP17A1GLSHDAC3HDAC8 | |
| SCHEMBL6404856 | 0.85 | CYP17A1 (0.56) | DRD2CYP17A1NAMPTGLSPTGDR2 | |
| SCHEMBL1314199 | 0.84 | CYP17A1 (0.54) | DRD2CYP17A1NAMPTGLSPTGDR2 | |
| SCHEMBL2244813 | 0.82 | CYP17A1 (0.58) | DRD2CYP17A1NAMPTGLSPTGDR2 | |
| SCHEMBL15014088 | 0.77 | NPC1 (0.62) | DRD2CYP17A1GLSPTGDR2 | |
| SCHEMBL16246084 | 0.77 | CYP17A1 (0.58) | DRD2CYP17A1NAMPTGLSPTGDR2 | |
| SCHEMBL12677009 | 0.77 | CYP17A1 (0.58) | DRD2CYP17A1NAMPTGLSPTGDR2 | |
| SCHEMBL27493682 | 0.77 | CYP17A1 (0.58) | DRD2CYP17A1NAMPTGLSPTGDR2 | |
| SCHEMBL245094 | 0.76 | CYP17A1 (0.61) | DRD2CYP17A1NAMPTGLSPTGDR2 | |
| SCHEMBL13181089 | 0.76 | HPGD (0.57) | DRD2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127130-A1 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-05-08 | — | — | US | disclosed |
| US-8629299-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-01-14 | — | — | US | disclosed |
| US-20130259802-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2013-10-03 | — | — | US | disclosed |
| US-8445721-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-20120171117-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2012-07-05 | — | — | US | disclosed |
| US-8148575-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-20090087379-A1 | Radiofluorinated Compounds and their Preparation | HAMMERSMITH IMANET LIMITED (GB) | 2009-04-02 | — | — | US | disclosed |
| WO-2007122488-A2 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087379-A1 | Radiofluorinated Compounds and their Preparation | PSMA5, MPI, PSMA3 | DRD2 4574/4885CYP17A1 3845/4885HRH3 3579/4885 |
| US-20120171117-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | PSMA5, MPI, PSMA3 | DRD2 4574/4885CYP17A1 3845/4885HRH3 3579/4885 |
| US-20140127130-A1 | Radiofluorinated compounds and their preparation | PSMA5, MPI, PSMA3 | DRD2 4574/4885CYP17A1 3845/4885HRH3 3579/4885 |
| US-20130259802-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | PSMA5, MPI, PSMA3 | DRD2 4574/4885CYP17A1 3845/4885HRH3 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.