Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | DRD2 | P14416 | 5/20 | 0.71 |
| ▸ | CCR5 | P51681 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 3/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | CCR3 | P51677 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755777 | 0.91 | MEN1 (0.68) | MEN1KMT2ADRD2CCR5SIGMAR1 | |
| SCHEMBL6023725 | 0.91 | MEN1 (0.68) | MEN1KMT2ADRD2CCR5SIGMAR1 | |
| SCHEMBL3598146 | 0.91 | MEN1 (0.68) | MEN1KMT2ADRD2CCR5SIGMAR1 | |
| SCHEMBL7571134 | 0.90 | MEN1 (0.88) | MEN1KMT2ADRD2CCR5DRD4 | |
| SCHEMBL9070278 | 0.90 | MEN1 (0.67) | MEN1KMT2ADRD2CCR5DRD4 | |
| SCHEMBL8659907 | 0.88 | MEN1 (0.65) | MEN1KMT2ADRD2CCR5DRD4 | |
| SCHEMBL8775737 | 0.88 | MEN1 (0.74) | MEN1KMT2ADRD2CCR5DRD4 | |
| SCHEMBL6701595 | 0.88 | KMT2A (0.65) | MEN1KMT2ADRD2CCR5DRD4 | |
| SCHEMBL2588250 | 0.88 | MEN1 (0.65) | MEN1KMT2ADRD2CCR5DRD4 | |
| SCHEMBL19222078 | 0.88 | MEN1 (0.74) | MEN1KMT2ADRD2CCR5DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105797140-A | Stable formulations of an acetyl hyaluronan-degrading enzyme | 哈洛齐梅公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-103974715-A | Stable formulations of hyaluronan degrading enzymes | HALOZYME INC | 2014-08-06 | — | — | CN | disclosed |
| WO-2011037771-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISM | MERCK SHARP & DOHME CORP. (US) | 2011-03-31 | — | — | WO | disclosed |
| CN-101981025-A | Diarylmethylamide derivative having antagonistic activity on melanin-concentrating hormone receptor | BANYU PHARMA CO LTD | 2011-02-23 | — | — | CN | disclosed |
| US-20110015198-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISM | BANYU PHARMACEUTICAL CO., INC. | 2011-01-20 | — | — | US | disclosed |
| EP-0743940-B1 | NEW COMPOUNDS WITH ANALGESIC AND LOCAL ANAESTHETIC EFFECT | ASTRA AB (SE) | 2000-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015198-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISM | MC1R, MCHR2, MCHR1 | MEN1 386/4885KMT2A 377/4885DRD2 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.