Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 6/20 | 1.00 |
| ▸ | AGL | P35573 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | GBA1 | P04062 | 2/20 | 1.00 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 1.00 |
| ▸ | MGAM | O43451 | 5/20 | 0.93 |
| ▸ | FUCA1 | P04066 | 5/20 | 0.93 |
| ▸ | GANC | Q8TET4 | 2/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19745374 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL19557590 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL15593220 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL13317732 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL14268489 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL4319863 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL2435520 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL466573 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL13848041 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 | |
| SCHEMBL2434435 | 1.00 | GLA (1.00) | GLAAGLGAAGBA1GBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273788-B2 | Five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis therapeutics | Academia Sinica, Taiwan (TW) | 2012-09-25 | — | — | US | disclosed |
| US-20120046337-A1 | Novel Five-Membered Iminocyclitol Derivatives as Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis Therapeutics | ACADEMIA SINICA | 2012-02-23 | — | — | US | disclosed |
| US-7919521-B2 | Five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis therapeutics | ACADEMIA SINICA (TW) | 2011-04-05 | — | — | US | disclosed |
| US-20090306174-A1 | Novel Five-Membered Iminocyclitol Derivatives as Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis Therapeutics | ACADEMIA SINICA (TW) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306174-A1 | Novel Five-Membered Iminocyclitol Derivatives as Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis Therapeutics | ACE2, ENGASE, DPP7 | GLA 31/4885AGL 161/4885GAA 27/4885 |
| US-20120046337-A1 | Novel Five-Membered Iminocyclitol Derivatives as Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis Therapeutics | ACE2, ENGASE, DPP7 | GLA 31/4885AGL 161/4885GAA 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.