Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029476 | 0.87 | MAPT (0.36) | MAPTMEN1KMT2AL3MBTL1CA12 | |
| SCHEMBL12982380 | 0.83 | MAPT (0.37) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL17856432 | 0.80 | CA12 (0.44) | MAPTMEN1KMT2AL3MBTL1CA12 | |
| SCHEMBL10028245 | 0.79 | MAPT (0.35) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL10029430 | 0.78 | MAPT (0.43) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL13512936 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL14879067 | 0.76 | MAPT (0.33) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL13014597 | 0.76 | GAA (0.30) | MAPTGAA | |
| SCHEMBL13015092 | 0.74 | MAPT (0.32) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL16429376 | 0.74 | CA12 (0.45) | MAPTMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251387-B1 | Acidic azo dyes | CLARIANT INT LTD (CH) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010130386-A1 | ACIDIC AZO DYES | CLARIANT INTERNATIONAL LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
| EP-2251387-A1 | Acidic azo dyes | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |