SCHEMBL10029682

SCHEMBL10029682

O=C(c1nc2ccccc2n1-c1ccccc1)c1nc2ccccc2n1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.56
HTT P42858 1/20 0.56
RECQL P46063 3/20 0.55
ALDH1A1 P00352 6/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
TSHR P16473 4/20 0.52
CRHBP P24387 2/20 0.52
CRHR2 Q13324 2/20 0.52
SLC22A12 Q96S37 1/20 0.52
USP2 O75604 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PPARG P37231 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
NPSR1 Q6W5P4 3/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 2/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2334505 0.89 RECQL (0.59) MAPK1HTTRECQLALDH1A1MEN1
SCHEMBL6581345 0.83 RECQL (0.50) MAPK1HTTRECQLALDH1A1MEN1
SCHEMBL17470433 0.79 MAPK1 (0.57) MAPK1HTTRECQLALDH1A1MEN1
SCHEMBL14505847 0.78 MAPK1 (0.56) MAPK1HTTRECQLALDH1A1MEN1
SCHEMBL18820626 0.78 MAPK1 (0.56) MAPK1HTTRECQLALDH1A1MEN1
SCHEMBL24790541 0.77 MAPK1 (0.50) MAPK1HTTRECQLALDH1A1MEN1
SCHEMBL13196540 0.76 MAPK1 (0.49) MAPK1HTTRECQLALDH1A1MEN1
SCHEMBL12252055 0.76 MAPK1 (0.61) MAPK1HTTRECQLALDH1A1MEN1
Bicarbonate SCHEMBL28889268 0.75 ESR1 (0.72) MAPK1HTTRECQLMEN1KMT2A
SCHEMBL28243421 0.75 MEN1 (0.56) MAPK1HTTRECQLALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed