SCHEMBL10030026

SCHEMBL10030026

c1ccc(-c2ccccc2-c2ccc3c(-c4cccc(-c5ccccn5)c4)c4ccccc4c(-c4cccc(-c5ccccn5)c4)c3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 3/20 0.44
PRKDC P78527 1/20 0.42
KDR P35968 1/20 0.40
DHODH Q02127 1/20 0.39
PDK2 Q15119 1/20 0.39
BRD4 O60885 1/20 0.39
PRMT5 O14744 2/20 0.39
WDR77 Q9BQA1 1/20 0.39
TGFBR1 P36897 2/20 0.38
PIM1 P11309 1/20 0.38
PIM3 Q86V86 1/20 0.38
HTR1A P08908 1/20 0.37
HTR7 P34969 1/20 0.37
CYP2A6 P11509 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
RET P07949 1/20 0.37
TLR4 O00206 1/20 0.36
TLR2 O60603 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10030036 0.94 KDR (0.40) GRM5PRKDCKDRDHODHPDK2
SCHEMBL10030029 0.92 DHODH (0.44) GRM5KDRDHODHPDK2PRMT5
SCHEMBL10030031 0.90 DHODH (0.42) GRM5KDRDHODHPRMT5WDR77
SCHEMBL10030020 0.90 DHODH (0.42) GRM5KDRDHODHPRMT5WDR77
SCHEMBL10030051 0.90 DHODH (0.42) GRM5KDRDHODHPRMT5WDR77
SCHEMBL10030063 0.89 KDM4E (0.45) PRKDCDHODHPDK2BRD4PRMT5
SCHEMBL10030042 0.89 DHODH (0.42) GRM5KDRDHODHPDK2PRMT5
SCHEMBL10030044 0.89 DHODH (0.41) GRM5PRKDCDHODHPRMT5WDR77
SCHEMBL17877067 0.89 DHODH (0.41) GRM5PRKDCDHODHPRMT5WDR77
SCHEMBL21266817 0.88 KDR (0.43) GRM5PRKDCKDRDHODHPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9860960-B2 Organic EL display device and method for production of the same JOLED INC. (JP) 2018-01-02 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-9024521-B2 Organic EL display device and method of manufacturing the same SONY CORPORATION (JP) 2015-05-05 US disclosed
US-9024521-B2 Organic EL display device and method of manufacturing the same SONY CORPORATION (JP) 2015-05-05 US disclosed
US-8823255-B2 Organic el display device and method of manufacturing the same SONY CORPORATION (JP) 2014-09-02 US disclosed
US-8823255-B2 Organic el display device and method of manufacturing the same SONY CORPORATION (JP) 2014-09-02 US disclosed
US-20130183781-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2013-07-18 US disclosed
US-20130183781-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2013-07-18 US disclosed
US-20120187386-A1 ORGANIC ELECTRO LUMINESCENCE DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME SONY CORPORATION (JP) 2012-07-26 US disclosed
US-20120187386-A1 ORGANIC ELECTRO LUMINESCENCE DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME SONY CORPORATION (JP) 2012-07-26 US disclosed
US-20120112173-A1 ORGANIC EL DISPLAY DEVICE AND METHOD FOR PRODUCTION OF THE SAME SONY CORPORATION (JP) 2012-05-10 US disclosed
US-20120112173-A1 ORGANIC EL DISPLAY DEVICE AND METHOD FOR PRODUCTION OF THE SAME SONY CORPORATION (JP) 2012-05-10 US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 US disclosed