Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | MAPK13 | O15264 | 1/20 | 1.00 |
| ▸ | MAPK12 | P53778 | 1/20 | 1.00 |
| ▸ | MAPK11 | Q15759 | 1/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | AHR | P35869 | 1/20 | 0.65 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365738 | 1.00 | NPC1 (1.00) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4227502 | 1.00 | NPC1 (1.00) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL30293252 | 0.98 | NPC1 (0.96) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL20073842 | 0.94 | NPC1 (0.88) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| Bicarbonate SCHEMBL9232742 | 0.92 | NPC1 (0.85) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| Oxalic Acid SCHEMBL8183265 | 0.90 | NPC1 (0.81) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| Alcohol SCHEMBL10571326 | 0.89 | NPC1 (0.79) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10364874 | 0.87 | NPC1 (0.76) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10800430 | 0.87 | NPC1 (0.76) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2138422 | 0.87 | MAPT (0.92) | NPC1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6104 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768675-B1 | NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORP (KR) | 2026-04-01 | — | — | EP | claimed |
| US-20250388599-A1 | TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2025-12-25 | — | — | US | claimed |
| US-12479838-B2 | D3 receptor agonist compounds; methods of preparation; intermediates thereof; and methods of use thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-11-25 | — | — | US | claimed |
| US-20250313535-A1 | ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2025-10-09 | — | — | US | claimed |
| EP-4580404-A2 | SULFONAMIDE APYRASE INHIBITORS | Texas Crop Science, Inc. (US) | 2025-07-09 | — | — | EP | claimed |
| WO-2025067486-A1 | QUINOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州旺山旺水生物医药股份有限公司 | 2025-04-03 | — | — | WO | claimed |
| EP-4522589-A1 | ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF | Dice Molecules Sv, Inc. (US) | 2025-03-19 | — | — | EP | claimed |
| CN-119390648-A | Dihydro quinolinone compounds and application thereof | 江门市中心医院 | 2025-02-07 | — | — | CN | claimed |
| CN-119330880-A | Method for preparing quinolinone series compounds by dehydrogenating dihydroquinolinone series compounds | 河南中医药大学 | 2025-01-21 | — | — | CN | claimed |
| CN-118852104-A | Dihydro-quinoline-2-ketone compound and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-10-29 | — | — | CN | claimed |
| EP-0166533-A1 | Quinolone inotropic agents | Pfizer Limited (GB) | 1986-01-02 | — | — | EP | claimed |
| EP-0148623-A2 | Quinolone inotropic agents | Pfizer Limited (GB) | 1985-07-17 | — | — | EP | claimed |
| US-4450165-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS; MYOCARDIAL AND CEREBRAL SYNDROMES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| EP-0003771-B1 | CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-10-20 | — | — | EP | claimed |
| EP-0052016-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-19 | — | — | EP | claimed |
| US-4329468-A | ADRENERGIC BLOCKING AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-11 | — | — | US | claimed |
| US-4256890-A | ADRENERGIC BLOCKING AGENTS | OTSUKAPHARMACEUTICAL CO., LTD. (JP) | 1981-03-17 | — | — | US | claimed |
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | claimed |
| US-4147869-A | ADRENERGIC BLOCKING AGENTS FOR TREATMENT OF ANGINA PECTORIS, ARRHYTHMIA AND HYPERTENSION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |
| US-3969507-A | 5-(HYDROXY-3-TERT-BUTYLAMINO)PROPOXY-3,4-DIHYDROCARBOSTYRIL | OTSUKA PHARMACEUTICAL COMPANY LIMITED (JA) | 1976-07-13 | — | — | US | claimed |