Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.75 |
| ▸ | TP53 | P04637 | 9/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 8/20 | 0.72 |
| ▸ | RORC | P51449 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | EEF2K | O00418 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429837 | 0.99 | MAPT (0.74) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL424784 | 0.98 | MAPT (0.72) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL13186366 | 0.88 | MAPT (0.81) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL18537666 | 0.87 | MAPT (0.80) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL22542452 | 0.87 | MAPT (0.79) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL14969370 | 0.87 | MAPT (0.80) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL426553 | 0.87 | MAPT (0.80) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL22542446 | 0.86 | MAPT (0.82) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL10134578 | 0.86 | MAPT (0.81) | MAPTTP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL426251 | 0.86 | MAPT (0.78) | MAPTTP53SMN1; SMN2RXFP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142682-A1 | ANTIVIRULENCE COMPOUNDS INHIBITING BACTERIAL MONO-ADP-RIBOSYLTRANSFERASE TOXINS | UNIVERSITY OF GUELPH (CA) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142682-A1 | ANTIVIRULENCE COMPOUNDS INHIBITING BACTERIAL MONO-ADP-RIBOSYLTRANSFERASE TOXINS | TIPARP, CD38, PARP14 | MAPT 1914/4885TP53 2170/4885SMN1; SMN2 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.