Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2377209 | 1.00 | BTK (0.71) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL4944886 | 0.87 | BTK (0.66) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL12519554 | 0.87 | BTK (0.66) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL15584829 | 0.87 | BTK (0.66) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL15499671 | 0.86 | BTK (0.54) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL668339 | 0.86 | BTK (0.54) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL7205713 | 0.84 | BTK (0.78) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL14502820 | 0.84 | BTK (0.78) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL7210932 | 0.84 | BTK (0.78) | BTKCA1CA2GAAKMT2A | |
| SCHEMBL7212396 | 0.84 | BTK (0.78) | BTKCA1CA2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024009206-A1 | A PROCESS FOR THE PREPARATION OF EDOXABAN AND ITS INTERMEDIATES | AMI LIFESCIENCES PRIVATE LIMITED (IN) | 2024-01-11 | — | — | WO | disclosed |
| EP-2980067-B1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-2980090-A1 | METHOD FOR PRODUCING (1S,4S,5S)-4-BROMO-6-OXABICYCLO[3.2.1]OCTAN-7-ONE | Daiichi Sankyo Co., Ltd. (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-20120035369-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035369-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-09 | — | — | US | disclosed |
| EP-2407457-A1 | PROCESS FOR PRODUCING DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035369-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | F12, DAO, TFPI | BTK 893/4885CA1 446/4885CA2 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.