Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035051 | 0.85 | MCHR1 (0.49) | MCHR1KLK7STAT3POLBMAPT | |
| SCHEMBL10035032 | 0.85 | MAPT (0.49) | MCHR1KLK7STAT3POLBMAPT | |
| SCHEMBL10035061 | 0.83 | F10 (0.47) | MCHR1KLK7STAT3POLBMAPT | |
| SCHEMBL10035033 | 0.82 | NPC1 (0.47) | MCHR1KLK7STAT3POLBMAPT | |
| SCHEMBL10034973 | 0.79 | STAT3 (0.46) | MCHR1KLK7STAT3POLBMAPT | |
| SCHEMBL10035265 | 0.79 | HTR1D (0.52) | MCHR1KLK7STAT3MAPTHTR2C | |
| SCHEMBL10035001 | 0.78 | STAT3 (0.55) | KLK7USP2STAT3MAPT | |
| SCHEMBL10035062 | 0.78 | ABCB1 (0.55) | KLK7USP2STAT3POLBMAPT | |
| SCHEMBL10034987 | 0.77 | F10 (0.49) | STAT3POLBMAPTF10 | |
| SCHEMBL14914055 | 0.77 | POLB (0.49) | MCHR1KLK7STAT3POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012008435-A1 | BIARYL AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 大日本住友製薬株式会社 (JP) | 2012-01-19 | — | — | WO | disclosed |