SCHEMBL10035694

SCHEMBL10035694

C[C@H](N)C(=O)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12267290 1.00
SCHEMBL10037283 1.00
Hydrochloric Acid SCHEMBL31503297 0.97 GAA (0.36)
Hydrochloric Acid SCHEMBL31503358 0.97 GAA (0.36)
SCHEMBL23897025 0.79
SCHEMBL12420361 0.77 SLC7A5 (0.50)
SCHEMBL14884433 0.77 SLC7A5 (0.50)
SCHEMBL12028795 0.77 SLC7A5 (0.50)
SCHEMBL1863987 0.75
SCHEMBL25015389 0.75 SLC7A5 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833167-B2 Nicotinyl riboside compounds and their uses MITOPOWER LLC (US) 2023-12-05 US disclosed
US-11833167-B2 Nicotinyl riboside compounds and their uses MITOPOWER LLC (US) 2023-12-05 US disclosed
US-20230348493-A1 COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO. LTD. (CN) 2023-11-02 US disclosed
WO-2023212019-A1 PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2023-11-02 WO disclosed
US-20230348506-A1 MACROCYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) 2023-11-02 US disclosed
US-11786605-B2 Site specific antibody-drug conjugates with peptide-containing linkers MERSANA THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
US-11786605-B2 Site specific antibody-drug conjugates with peptide-containing linkers MERSANA THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
US-20230255995-A1 Nicotinyl Riboside Compounds and Their Uses MITOPOWER LLC 2023-08-17 US disclosed
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 US disclosed
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 US disclosed
US-20130309192-A1 Auristatin Compounds and Conjugates Thereof MERSANA THERAPEUTICS, INC. (US) 2013-11-21 US disclosed
US-20130101546-A1 Protein-Polymer-Drug Conjugates MERSANA THERAPEUTICS, INC. (US) 2013-04-25 US disclosed
US-20130045935-A1 FLAVONOID DIMERS AND THEIR USE THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2013-02-21 US disclosed
US-20120321583-A1 Protein-Polymer-Drug Conjugates MERSANA THERAPEUTICS, INC. (US) 2012-12-20 US disclosed
US-20120077711-A1 Novel Ligands and Libraries of Ligands SUNESIS PHARMACEUTICALS, INC. (US) 2012-03-29 US disclosed
US-20120077711-A1 Novel Ligands and Libraries of Ligands SUNESIS PHARMACEUTICALS, INC. (US) 2012-03-29 US disclosed
US-8119653-B2 Belactosin derivatives as therapeutic agents/biological probes and their synthesis THE TEXAS A&M UNIVERSITY SYSTEM (US) 2012-02-21 US disclosed
US-20110301192-A1 Inhibitors of Cyclin Kinase Inhibitor p21 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-12-08 US disclosed
US-20110172193-A1 PRO-DRUGS OF (E)-7-(3-(2-AMINO-1-FLUOROETHYLIDENE)PIPERIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID JANSSEN PHARMACEUTICA NV (BE) 2011-07-14 US disclosed
US-20090042922-A1 NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS NATIONAL SCIENCE FOUNDATION 2009-02-12 US disclosed