⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22421289 | 0.67 | — | — | |
| SCHEMBL28916432 | 0.67 | — | — | |
| SCHEMBL23191928 | 0.62 | — | — | |
| SCHEMBL18951772 | 0.62 | — | — | |
| SCHEMBL13213449 | 0.60 | — | — | |
| SCHEMBL28307900 | 0.59 | — | — | |
| SCHEMBL18812130 | 0.58 | — | — | |
| SCHEMBL17429849 | 0.57 | — | — | |
| SCHEMBL24719961 | 0.57 | — | — | |
| SCHEMBL13863852 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093210-B2 | Treatment of sepsis with 5-ethyl-1-phenyl-2(1H)-pyridone | SOLANAN, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110092549-A1 | Treatment of Sepsis with 5-Ethyl-1-Phenyl-2(1H)-Pyridone | SOLANAN, INC. (US) | 2011-04-21 | — | — | US | disclosed |