Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.83 |
| ▸ | MEN1 | O00255 | 9/20 | 0.83 |
| ▸ | RAB9A | P51151 | 9/20 | 0.83 |
| ▸ | HTT | P42858 | 8/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.83 |
| ▸ | POLB | P06746 | 6/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.83 |
| ▸ | BLM | P54132 | 4/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.83 |
| ▸ | LMNA | P02545 | 4/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.83 |
| ▸ | PPARG | P37231 | 3/20 | 0.83 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.83 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.83 |
| ▸ | APP | P05067 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | THRB | P10828 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31018271 | 0.92 | KMT2A (0.97) | KMT2AMEN1RAB9AHTTNPSR1 | |
| SCHEMBL5676065 | 0.92 | KMT2A (0.97) | KMT2AMEN1RAB9AHTTNPSR1 | |
| SCHEMBL5676060 | 0.92 | KMT2A (0.97) | KMT2AMEN1RAB9AHTTNPSR1 | |
| Iodide SCHEMBL29473159 | 0.91 | KMT2A (1.00) | KMT2AMEN1RAB9AHTTNPSR1 | |
| Iodide SCHEMBL124471 | 0.91 | KMT2A (1.00) | KMT2AMEN1RAB9AHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL11551422 | 0.91 | KMT2A (0.95) | KMT2AMEN1RAB9AHTTNPSR1 | |
| Iodide SCHEMBL124472 | 0.91 | KMT2A (1.00) | KMT2AMEN1RAB9AHTTNPSR1 | |
| Perchlorate SCHEMBL4877794 | 0.88 | KMT2A (0.88) | KMT2AMEN1RAB9AHTTNPSR1 | |
| Perchlorate SCHEMBL4877802 | 0.88 | KMT2A (0.88) | KMT2AMEN1RAB9AHTTNPSR1 | |
| SCHEMBL2948028 | 0.87 | KMT2A (0.67) | KMT2AMEN1RAB9AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | SNCA, PSEN1, CDR2 | KMT2A 2624/4885MEN1 2218/4885RAB9A 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.