Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.44 |
| ▸ | PRKCG | P05129 | 3/20 | 0.44 |
| ▸ | PRKCB | P05771 | 3/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.44 |
| ▸ | PRKCH | P24723 | 3/20 | 0.44 |
| ▸ | PRKCI | P41743 | 3/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518663 | 1.00 | PRKD3 (0.44) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL25125557 | 0.91 | TSHR (0.39) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL18348901 | 0.84 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL25936133 | 0.83 | PRKD3 (0.39) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11080097 | 0.81 | PRKD3 (0.47) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11081240 | 0.81 | PRKD3 (0.47) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11238111 | 0.81 | EPHX1 (0.36) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11082840 | 0.81 | PRKD3 (0.43) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL15271411 | 0.79 | PRKD3 (0.48) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL15271057 | 0.79 | PRKD3 (0.48) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120080340-A1 | STAPLE CARTRIDGE COMPRISING A VARIABLE THICKNESS COMPRESSIBLE PORTION | ETHICON ENDO-SURGERY, INC. (US) | 2012-04-05 | — | — | US | disclosed |