Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005316 | 0.85 | BACE1 (0.41) | MAPTCYP1A2BACE1ALDH1A1KMT2A | |
| SCHEMBL3300391 | 0.77 | BACE1 (0.66) | MAPTCYP1A2BACE1ALDH1A1KMT2A | |
| SCHEMBL13866648 | 0.73 | KDM4E (0.47) | BACE1KDM4EGAAATML3MBTL1 | |
| SCHEMBL21131815 | 0.73 | KDM4E (0.43) | KDM4EATML3MBTL1KIF11 | |
| SCHEMBL21132054 | 0.73 | KDM4E (0.43) | KDM4EATML3MBTL1KIF11 | |
| SCHEMBL21132055 | 0.73 | KDM4E (0.43) | KDM4EATML3MBTL1KIF11 | |
| SCHEMBL21131814 | 0.73 | KDM4E (0.43) | KDM4EATML3MBTL1KIF11 | |
| SCHEMBL17563165 | 0.71 | KDM4E (0.42) | ALDH1A1KMT2AKDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL19270032 | 0.71 | KDM4E (0.42) | KDM4EATML3MBTL1KIF11 | |
| SCHEMBL19270916 | 0.71 | KDM4E (0.42) | KDM4EATML3MBTL1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106206-B2 | Solid luminescent quinoline compounds | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20110263861-A1 | QUINOLINE COMPOUND | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263861-A1 | QUINOLINE COMPOUND | GTF3C3, GTF3C2, GTF3C1 | MAPT 3796/4885CYP1A2 666/4885BACE1 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.