Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.65 |
| ▸ | TNKS | O95271 | 3/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039893 | 0.98 | PARP1 (0.65) | PARP1TNKSTNKS2 | |
| SCHEMBL10039875 | 0.89 | PARP1 (0.69) | PARP1 | |
| SCHEMBL10039877 | 0.88 | PARP1 (0.58) | PARP1TNKSTNKS2 | |
| SCHEMBL10039821 | 0.88 | PARP1 (0.58) | PARP1TNKSTNKS2 | |
| SCHEMBL10039736 | 0.87 | PARP1 (0.69) | PARP1 | |
| SCHEMBL10039709 | 0.87 | PARP1 (0.62) | PARP1TNKSTNKS2 | |
| SCHEMBL10039782 | 0.87 | PARP1 (0.60) | PARP1TNKSTNKS2 | |
| SCHEMBL10039811 | 0.86 | PARP1 (0.59) | PARP1TNKSTNKS2 | |
| SCHEMBL10039754 | 0.86 | PARP1 (0.66) | PARP1 | |
| SCHEMBL10039894 | 0.86 | PARP1 (0.57) | PARP1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019430-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |