Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039744 | 1.00 | PARP1 (0.61) | PARP1 | |
| SCHEMBL10039819 | 1.00 | PARP1 (0.61) | PARP1 | |
| SCHEMBL10039750 | 0.87 | PARP1 (0.61) | PARP1 | |
| SCHEMBL10039739 | 0.87 | PARP1 (0.65) | PARP1 | |
| SCHEMBL10039732 | 0.87 | PARP1 (0.63) | PARP1 | |
| SCHEMBL10039784 | 0.87 | PARP1 (0.65) | PARP1 | |
| SCHEMBL10039730 | 0.87 | PARP1 (0.63) | PARP1 | |
| SCHEMBL10039680 | 0.86 | PARP1 (0.64) | PARP1 | |
| SCHEMBL10039753 | 0.86 | PARP1 (0.66) | PARP1 | |
| SCHEMBL10039693 | 0.86 | PARP1 (0.62) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019430-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |