Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Calindol SCHEMBL29455078 | 0.84 | CASR (1.00) | CASR | |
| Calindol SCHEMBL4108222 | 0.84 | CASR (1.00) | CASR | |
| Calindol SCHEMBL4100568 | 0.84 | CASR (1.00) | CASR | |
| Calindol SCHEMBL4103949 | 0.84 | CASR (1.00) | CASR | |
| SCHEMBL10039779 | 0.83 | CASR (0.80) | CASR | |
| SCHEMBL4107517 | 0.83 | CASR (0.80) | CASR | |
| Calindol SCHEMBL18210366 | 0.83 | CASR (1.00) | CASR | |
| Calindol SCHEMBL2702603 | 0.83 | CASR (1.00) | CASR | |
| SCHEMBL4116319 | 0.82 | CASR (0.78) | CASR | |
| SCHEMBL10039655 | 0.82 | CASR (0.78) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084971-A1 | INDOLE DERIVATIVES AS AGENTS AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-06-28 | — | — | WO | disclosed |