Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10040444 | 0.96 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13107565 | 0.95 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18472499 | 0.95 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18699003 | 0.94 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12082427 | 0.94 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13107535 | 0.92 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18649377 | 0.92 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18698939 | 0.91 | TSHR (0.43) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18699034 | 0.91 | TSHR (0.43) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18472502 | 0.91 | TSHR (0.43) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548586-B1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH FLAT OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2020-09-23 | — | — | EP | disclosed |
| US-20170226421-A1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| US-RE46426-E1 | Birefringent polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| WO-2016020035-A1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2016-02-11 | — | — | WO | disclosed |
| US-8697199-B2 | Calamitic mesogenic compounds | MERCK PATENT GMBH (DE) | 2014-04-15 | — | — | US | disclosed |
| US-8697199-B2 | Calamitic mesogenic compounds | MERCK PATENT GMBH (DE) | 2014-04-15 | — | — | US | disclosed |
| EP-2494004-B1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2013-09-25 | — | — | EP | disclosed |
| US-8470198-B2 | Mesogenic compounds comprising discotic and calamitic groups | MERCK PATENT GMBH (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470198-B2 | Mesogenic compounds comprising discotic and calamitic groups | MERCK PATENT GMBH (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8323527-B2 | Fluorene derivatives | MERCK PATENT GMBH (DE) | 2012-12-04 | — | — | US | disclosed |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PARRI OWAIN LLYR | 2010-05-06 | — | — | US | disclosed |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PARRI OWAIN LLYR | 2010-05-06 | — | — | US | disclosed |
| US-20100072422-A1 | Birefringent Layer with Negative Optical Dispersion | MERCK PATENT GMBH (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100072422-A1 | Birefringent Layer with Negative Optical Dispersion | MERCK PATENT GMBH (DE) | 2010-03-25 | — | — | US | disclosed |
| WO-2010020312-A1 | MESOGENIC COMPOUNDS COMPRISING DISCOTIC AND CALAMITIC GROUPS | MERCK PATENT GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |
| WO-2009039937-A1 | MESOGENIC DIMERS | MERCK PATENT GMBH (DE) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009030332-A1 | CALAMITIC MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009030352-A1 | FLUORENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
| WO-2008119426-A1 | BIREFINGENT LAYER WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119427-A1 | BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PUF60, LCP1, MAP1LC3C | TSHR 4787/4885ALDH1A1 4619/4885CYP3A4 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.