Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385091 | 0.74 | TSHR (0.46) | TSHRTDP1RGS12BACE1 | |
| SCHEMBL11390371 | 0.68 | TSHR (0.41) | TSHRTDP1RGS12BACE1 | |
| SCHEMBL1727964 | 0.67 | — | — | |
| Water SCHEMBL11036981 | 0.67 | TSHR (0.39) | TSHRTDP1RGS12BACE1 | |
| SCHEMBL8148062 | 0.64 | IDUA (0.39) | TSHRTDP1RGS12 | |
| SCHEMBL11771126 | 0.64 | TSHR (0.41) | TSHRTDP1 | |
| SCHEMBL11816855 | 0.64 | TSHR (0.41) | TSHRTDP1 | |
| SCHEMBL2064740 | 0.62 | TSHR (0.39) | TSHRTDP1RGS12BACE1 | |
| SCHEMBL1653842 | 0.61 | TSHR (0.36) | TSHR | |
| SCHEMBL11283221 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029021-A1 | Nitroxide Free Radical Synergized Antineoplastic Agents | THE TRUSTEES OF CALIFORNIA STATE UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029021-A1 | Nitroxide Free Radical Synergized Antineoplastic Agents | NOX1, NQO1, TXNRD2 | TSHR 3708/4885TDP1 239/4885RGS12 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.