⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070299 | 0.69 | — | — | |
| SCHEMBL723776 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL21412256 | 0.60 | — | — | |
| SCHEMBL22436393 | 0.60 | — | — | |
| SCHEMBL8404471 | 0.60 | — | — | |
| SCHEMBL15741186 | 0.59 | — | — | |
| SCHEMBL12809903 | 0.59 | — | — | |
| SCHEMBL15262534 | 0.59 | — | — | |
| SCHEMBL16511917 | 0.59 | — | — | |
| SCHEMBL16651034 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586712-A | Novel compounds | 豪夫迈·罗氏有限公司 | 2026-02-27 | — | — | CN | claimed |
| EP-4615830-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-17 | — | — | EP | claimed |
| WO-2025026882-A1 | NOVEL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-02-06 | — | — | WO | claimed |
| WO-2024099993-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-16 | — | — | WO | claimed |
| CN-117794910-A | NLRP3 inhibitors | 豪夫迈·罗氏有限公司 | 2024-03-29 | — | — | CN | claimed |
| EP-4735429-A1 | TRIAZINE DERIVATIVES AS NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-06 | — | — | EP | disclosed |
| CN-121586712-A | Novel compounds | 豪夫迈·罗氏有限公司 | 2026-02-27 | — | — | CN | disclosed |
| EP-4615841-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-4615830-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-4609865-A2 | NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| WO-2025026882-A1 | NOVEL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-02-06 | — | — | WO | disclosed |
| WO-2025003288-A1 | TRIAZINE DERIVATIVES AS NLRP3 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-02 | — | — | WO | disclosed |
| WO-2024169858-A1 | SIX-MEMBERED NITROGEN HETEROCYCLIC COMPOUND AND USE THEREOF | 成都赜灵生物医药科技有限公司 | 2024-08-22 | — | — | WO | disclosed |
| WO-2024099992-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024099993-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-16 | — | — | WO | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-4337652-A1 | NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022238347-A1 | NLRP3 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-11-17 | — | — | WO | disclosed |
| US-20120022053-A1 | Oxadiazine Derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2065370-A1 | 2-cyanobenzene sulfonamides as pesticides | Bayer CropScience AG (DE) | 2009-06-03 | — | — | EP | disclosed |