Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 5/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | CDK1 | P06493 | 5/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041199 | 0.88 | CDK5 (0.39) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL10041195 | 0.87 | CDK5 (0.38) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL10070993 | 0.85 | CYP1A2 (0.43) | LTA4HKDM4E | |
| SCHEMBL10041197 | 0.85 | ERN1 (0.39) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL10041200 | 0.80 | AKR1B1 (0.35) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL10070478 | 0.78 | CDK5 (0.33) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL17736777 | 0.78 | GSK3B (0.45) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL4568721 | 0.78 | GSK3B (0.40) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL18827124 | 0.77 | CDK5 (0.57) | CDK5CDK5R1GSK3BCDK1CCNB1 | |
| SCHEMBL17736806 | 0.76 | MAPT (0.43) | CDK5CDK5R1GSK3BCDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120161089-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120161089-A1 | CHROMENE COMPOUND | CYP8B1, HSD3B2, CYP17A1 | CDK5 2524/4885CDK5R1 1160/4885GSK3B 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.