SCHEMBL10041260

SCHEMBL10041260

c1ccc(-c2nc3ccccc3n2-c2cccc(-n3c(-c4ccccc4)nc4ccccc43)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.67
ESR2 Q92731 1/20 0.67
GAA P10253 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
HDAC1 Q13547 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
GRIA1 P42261 1/20 0.52
CACNG8 Q8WXS5 1/20 0.52
CACNG2 Q9Y698 1/20 0.52
RECQL P46063 1/20 0.50
RPS6KB1 P23443 3/20 0.49
PRKACA P17612 1/20 0.49
GSK3B P49841 1/20 0.49
ROCK1 Q13464 1/20 0.49
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15446479 0.92 ESR1 (0.58) ESR1ESR2GAAMEN1KMT2A
SCHEMBL541157 0.91 ESR2 (0.78) ESR1ESR2GAAMEN1KMT2A
SCHEMBL25769018 0.91 ESR1 (0.60) ESR1ESR2GAAMEN1KMT2A
SCHEMBL22926671 0.91 ESR1 (0.60) ESR1ESR2GAAMEN1KMT2A
SCHEMBL15033629 0.91 ESR1 (0.60) ESR1ESR2GAAMEN1KMT2A
SCHEMBL13314056 0.90 ESR2 (0.67) ESR1ESR2GAAMEN1KMT2A
SCHEMBL29406589 0.89 ESR2 (0.76) ESR1ESR2GAAMEN1KMT2A
SCHEMBL28338917 0.89 ESR2 (0.76) ESR1ESR2GAAMEN1KMT2A
SCHEMBL30282233 0.89 ESR2 (0.76) ESR1ESR2GAAMEN1KMT2A
SCHEMBL27860194 0.89 ESR2 (0.76) ESR1ESR2GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8147987-B2 Organic electroluminescent element and compounds for use in the element FUJIFILM CORPORATION (JP) 2012-04-03 US disclosed
US-8147987-B2 Organic electroluminescent element and compounds for use in the element FUJIFILM CORPORATION (JP) 2012-04-03 US disclosed
US-20070202357-A1 Organic electroluminescent element and compounds for use in the element FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed
US-20070202357-A1 Organic electroluminescent element and compounds for use in the element FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070202357-A1 Organic electroluminescent element and compounds for use in the element RPL31, RPL38, RPL39 ESR1 73/4885ESR2 41/4885GAA 3516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.