SCHEMBL10042436

SCHEMBL10042436

CC(C)c1c(F)c(F)c(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23425489 0.97 ANPEP (0.31) ANPEPDPP4
SCHEMBL24282818 0.97 ANPEP (0.31) ANPEPDPP4
SCHEMBL20436764 0.97
SCHEMBL20436779 0.97
SCHEMBL18745535 0.92
SCHEMBL18746362 0.91
SCHEMBL18389166 0.91 ANPEP (0.31) ANPEPDPP4
SCHEMBL87230 0.90
SCHEMBL12912878 0.87
SCHEMBL12180002 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795953-B2 Organometallic catalysts BERGEN TEKNOLOGIOVERFORING AS (NO) 2017-10-24 US disclosed
US-20160214098-A1 NOVEL ORGANOMETALLIC CATALYSTS BERGEN TEKNOLOGIOVERFORING AS (NO) 2016-07-28 US disclosed
US-9303100-B2 Organometallic catalysts BERGEN TEKNOLOGIOVERFORING AS (NO) 2016-04-05 US disclosed
US-20150025212-A1 NOVEL ORGANOMETALLIC CATALYSTS BERGEN TEKNOLOGIOVERFORING AS (NO) 2015-01-22 US disclosed
EP-1640372-B1 1,4-BENZODIOXANE SULFONIC ACID COMPOUND AND USE THEREOF AS ELECTRON-ACCEPTOR MATERIAL NISSAN CHEMICAL IND LTD (JP) 2012-08-01 EP disclosed
US-8110636-B1 Multi-block sulfonated poly(phenylene) copolymer proton exchange membranes SANDIA CORPORATION (US) 2012-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160214098-A1 NOVEL ORGANOMETALLIC CATALYSTS ZKSCAN2, ZC3HAV1L, ZRANB2 ANPEP 4297/4885DPP4 3931/4885
US-20150025212-A1 NOVEL ORGANOMETALLIC CATALYSTS ZKSCAN2, ZC3HAV1L, ZRANB2 ANPEP 4297/4885DPP4 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.