⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1280041 | 0.73 | — | — | |
| SCHEMBL10269361 | 0.73 | — | — | |
| SCHEMBL12991332 | 0.72 | — | — | |
| SCHEMBL8348701 | 0.71 | — | — | |
| SCHEMBL12562103 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL30636037 | 0.69 | — | — | |
| SCHEMBL8214989 | 0.69 | — | — | |
| Ethylene SCHEMBL28608631 | 0.67 | — | — | |
| SCHEMBL18484283 | 0.67 | — | — | |
| SCHEMBL18687256 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135260-A1 | NOVEL AMINE-SUBSTITUTED PHTHALAZINES AND DERIVATIVES AS SOS1 INHIBITORS | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2023-07-20 | — | — | WO | disclosed |
| US-11576979-B2 | Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof | GENENTECH, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-20190175749-A1 | PYRROLOBENZODIAZEPINE PRODRUGS AND ANTIBODY CONJUGATES THEREOF | GENENTECH, INC. (US) | 2019-06-13 | — | — | US | disclosed |
| WO-2018031662-A1 | PYRROLOBENZODIAZEPINE PRODRUGS AND ANTIBODY CONJUGATES THEREOF | GENENTECH, INC. (US) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017124034-A1 | TRANSFER RNA LIGAND ADDUCT LIBRARIES | GALEN BIOTECHNOLOGIES, LLC (US) | 2017-07-20 | — | — | WO | disclosed |
| US-8349826-B2 | Oxazolidinone derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-01-08 | — | — | US | disclosed |
| US-20120141423-A1 | NOVEL PAENIBACILLUS POLYMYXA STRAIN, ANTIBIOTIC ANTIMICROBIAL AGENTS AND METHODS OF THEIR USE | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION | 2012-06-07 | — | — | US | disclosed |
| EP-2069473-B1 | ANTIBIOTIC ANTIMICROBIAL AGENTS AND METHODS OF THEIR USE | UNIV OHIO STATE RES FOUND (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20100331308-A1 | OXAZOLIDINONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-12-30 | — | — | US | disclosed |
| US-20100152460-A1 | PROCESS FOR THE PREPARATION OF OPIOID MODULATORS | CAI CHAOZHONG | 2010-06-17 | — | — | US | disclosed |
| US-20100036132-A1 | PROCESS FOR THE PREPARATION OF OPIOD MODULATORS | CAI CHAOZHONG | 2010-02-11 | — | — | US | disclosed |
| US-7629488-B2 | 2-tert-Butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethylphenyl)propionic acid; treatment and prevention of pain and gastrointestinal disorders; cost efficiency, industrial scale production | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-12-08 | — | — | US | disclosed |
| EP-2116251-A1 | Antibotic antimicrobial agents and methods of their use | The Ohio State University Research Foundation (US) | 2009-11-11 | — | — | EP | disclosed |
| US-7402407-B1 | Chemically targeted positional identification of post-translationally phosphorylated peptides | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-07-22 | — | — | US | disclosed |
| US-20070099256-A1 | Chemical derivatization, detection, and identification of peptide and protein modifications | Apricot Ideas, Inc. | 2007-05-03 | — | — | US | disclosed |
| US-20070087447-A1 | System and method of free radical initiated protein sequencing | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2007-04-19 | — | — | US | disclosed |