SCHEMBL10044360

SCHEMBL10044360

Cc1ccc(NC(=O)C(=O)N[C@@H]2CC[C@H](C(=O)N(C)C)C[C@H]2NC(=O)c2nc3c(s2)CN(C)CC3)nc1

nearest known ligand 0.85

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.85
F2 P00734 2/20 0.85
F5 P12259 1/20 0.85
PLAT P00750 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12036431 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL13379592 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL10044356 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL10044358 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL10044354 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL1253575 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL10044357 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL14198192 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL12761845 1.00 F10 (0.85) F10F2F5PLAT
SCHEMBL10044355 1.00 F10 (0.85) F10F2F5PLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120053349-A1 OXAMIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053349-A1 OXAMIDE DERIVATIVE SULT1E1, PKD2, PKD1 F10 1005/4885F2 107/4885F5 432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.