Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 13/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.46 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288631 | 0.93 | PIK3CG (0.59) | PIK3CGPIK3CDMAPTPIK3CAPIK3CB | |
| SCHEMBL2721975 | 0.90 | PIK3CG (0.63) | PIK3CGPIK3CDMAPTPIK3CAPIK3CB | |
| SCHEMBL2729713 | 0.89 | PIK3CD (0.67) | PIK3CGPIK3CDMAPT | |
| SCHEMBL4289089 | 0.88 | PIK3CD (0.65) | PIK3CGPIK3CDMAPT | |
| SCHEMBL2722050 | 0.88 | PIK3CG (0.55) | PIK3CGPIK3CDMAPTPIK3CAPIK3CB | |
| SCHEMBL2722453 | 0.88 | PIK3CG (0.63) | PIK3CGPIK3CDMAPTPIK3CAPIK3CB | |
| SCHEMBL10044927 | 0.86 | MAPT (0.55) | PIK3CGPIK3CDMAPTPIK3CAPIK3CB | |
| SCHEMBL10044538 | 0.86 | PIK3CG (0.48) | PIK3CGPIK3CDMAPTKMT2A | |
| SCHEMBL2732827 | 0.86 | PIK3CG (0.65) | PIK3CGPIK3CDMAPTPIK3CAPIK3CB | |
| SCHEMBL2730831 | 0.85 | PIK3CG (0.65) | PIK3CGPIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052420-A1 | METHOD FOR PREPARING SUBSTITUTED N-(3-AMINO-QUINOXALIN-2-YL)-SULFONAMIDES AND THEIR INTERMEDIATES N-(3-CHLORO-QUINOXALIN-2-YL)SULFONAMIDES | MERCK SERONO S.A. GENEVA (CH) | 2012-04-26 | — | — | WO | disclosed |