SCHEMBL10044875

SCHEMBL10044875

CC(=O)C#CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL609904 0.84
SCHEMBL4200 0.80
SCHEMBL9418842 0.80
SCHEMBL1331044 0.80
SCHEMBL9365433 0.79
SCHEMBL3887603 0.76
SCHEMBL29102226 0.76
SCHEMBL2838353 0.76
SCHEMBL11006633 0.76 CA1 (0.36)
Hydrochloric Acid SCHEMBL10411964 0.76 CA1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557600-B Sha Ku is than bent preparation method SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) 2016-05-04 CN claimed
CN-104557600-A Preparation method of sacubitril SUZHOU MIRACPHARMA TECHNOLOGY CO LTD 2015-04-29 CN claimed
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-20230287365-A1 COMPOSITIONS AND METHODS FOR DECREASING INFLAMMATION BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2023-09-14 US disclosed
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-01 US disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
CN-109384701-A It is a kind of to be used to prepare compound and the preparation method and application thereof of the Sha Ku than song 上海朴颐化学科技有限公司 2019-02-26 CN disclosed
CN-109071407-A Intermediate of shakubiqu and preparation method thereof 广东东阳光药业有限公司 2018-12-21 CN disclosed
CN-108727213-A One planting sand library must be bent preparation method 中国科学院上海有机化学研究所 2018-11-02 CN disclosed
US-20180217498-A1 PHOTOACTIVABLE NITROGEN BASES BASF SE (DE) 2018-08-02 US disclosed
US-9921477-B2 Photoactivable nitrogen bases BASE SE (DE) 2018-03-20 US disclosed
US-9770442-B2 Self-assembling amphiphilic polymers as anti-cancer agents ALLEXCEL INC. (US) 2017-09-26 US disclosed
CN-106977415-A One planting sand storehouse must be bent intermediate and preparation method thereof 广东东阳光药业有限公司 2017-07-25 CN disclosed
CN-104557600-B Sha Ku is than bent preparation method SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) 2016-05-04 CN disclosed
CN-104557600-B Sha Ku is than bent preparation method SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) 2016-05-04 CN disclosed
US-8778645-B2 Method for the production of glutaconate BASF SE (DE) 2014-07-15 US disclosed
US-20120021472-A1 Method for the Production of Glutaconate BASF SE (DE) 2012-01-26 US disclosed
EP-1673385-B1 MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS BOEHRINGER INGELHEIM INT (DE) 2011-03-02 EP disclosed
US-20100105794-A1 PHOTOACTIVABLE NITROGEN BASES CIBA CORPORATION (US) 2010-04-29 US disclosed