Oxirane

Oxirane

SCHEMBL1004512

C1CO1.c1ccc(OCC2CO2)cc1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.89
ALDH1A1 P00352 4/20 0.67
TP53 P04637 3/20 0.67
TSHR P16473 3/20 0.67
HIF1A Q16665 2/20 0.67
CYP3A4 P08684 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
MAPT P10636 2/20 0.54
HPGD P15428 2/20 0.54
PKM P14618 2/20 0.54
CYP1A2 P05177 1/20 0.54
PPARG P37231 1/20 0.54
LMNA P02545 1/20 0.54
GAA P10253 1/20 0.54
GLA P06280 1/20 0.53
HRH3 Q9Y5N1 1/20 0.51
PDK1 Q15118 2/20 0.49
DRD4 P21917 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL15602787 1.00 TDP1 (0.89) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL31220 0.94 TDP1 (1.00) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL1583161 0.94 TDP1 (1.00) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL17028904 0.94 TDP1 (1.00) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL1582872 0.94 TDP1 (1.00) TDP1ALDH1A1TP53TSHRHIF1A
Propylene Oxide SCHEMBL20547010 0.93 TDP1 (0.77) TDP1ALDH1A1TP53TSHRHIF1A
Methane SCHEMBL11454420 0.92 TDP1 (0.96) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL21178023 0.92 TDP1 (0.96) TDP1ALDH1A1TP53TSHRHIF1A
Iodide SCHEMBL9053819 0.92 TDP1 (0.96) TDP1ALDH1A1TP53TSHRHIF1A
Methane SCHEMBL28968045 0.92 TDP1 (0.96) TDP1ALDH1A1TP53TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3647367-B1 THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TORAY INDUSTRIES (JP) 2023-11-15 EP disclosed
US-11814545-B2 Conductive polymer dispersion and method for preparing same, and method for manufacturing conductive film SHIN-ETSU POLYMER CO., LTD. (JP) 2023-11-14 US disclosed
CN-114174427-B Flame retardant polybutylene terephthalate resin composition 宝理塑料株式会社 2023-08-15 CN disclosed
WO-2023145596-A1 THERMOPLASTIC POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCING THERMOPLASTIC POLYESTER RESIN COMPOSITION, AND MOLDED ARTICLE 東レ株式会社 2023-08-03 WO disclosed
EP-2681260-B2 METHOD FOR PRODUCING AN AQUEOUS DISPERSION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-31 EP disclosed
US-11661238-B2 Coated container device, method of making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-30 US disclosed
EP-3650496-B1 COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-03 EP disclosed
CN-111073401-B Coating composition 陶氏环球技术有限责任公司 2022-09-20 CN disclosed
CN-110551424-B Coating compositions and articles made therefrom 陶氏环球技术有限责任公司 2022-07-29 CN disclosed
US-20220227536-A1 COATED CONTAINER DEVICE, METHOD OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2022-07-21 US disclosed
CN-1180024-C Polyester composition and connector ������������ʽ���� 2004-12-15 CN disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed
US-20040102565-A1 Aqueous dispersion KURARAY CO., LTD. (JP) 2004-05-27 US disclosed
US-6610774-B2 Aqueous dispersion KURARAY CO., LTD. (JP) 2003-08-26 US disclosed
US-20020099150-A1 Polyester composition and connector TORAY INDUSTRIES, INC. (JP) 2002-07-25 US disclosed
CN-1354199-A Polyester composition and connector TORAY CORP (JP) 2002-06-19 CN disclosed
EP-1209200-A2 Polyester composition and connector TORAY INDUSTRIES, INC. (JP) 2002-05-29 EP disclosed
US-20020040098-A1 Aqueous dispersion KURARAY CO., LTD. (JP) 2002-04-04 US disclosed
EP-1172407-A2 Aqueous adhesive dispersion containing a block copolymer and a polyurethane KURARAY CO., LTD. (JP) 2002-01-16 EP disclosed