Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883642 | 0.81 | MALT1 (0.53) | GPR174GAAALDH1A1MAPTRECQL | |
| SCHEMBL18774148 | 0.73 | MALT1 (0.55) | GPR174GAAALDH1A1MAPTRECQL | |
| SCHEMBL5940309 | 0.70 | MEN1 (0.51) | GAASTAT3ALDH1A1MAPTRECQL | |
| SCHEMBL18771058 | 0.69 | MALT1 (0.42) | GAAALDH1A1MAPTRECQLKDM4E | |
| SCHEMBL12473165 | 0.65 | MALT1 (0.61) | GAAALDH1A1MAPTRECQLKDM4E | |
| SCHEMBL12473069 | 0.62 | MALT1 (0.65) | ALDH1A1MAPTRECQLKDM4EPOLB | |
| SCHEMBL18774056 | 0.62 | MALT1 (0.65) | ALDH1A1MAPTRECQLKDM4EPOLB | |
| SCHEMBL6033559 | 0.61 | MALT1 (0.53) | ALDH1A1MAPTRECQLKDM4EHTT | |
| SCHEMBL12473212 | 0.61 | MALT1 (0.68) | ALDH1A1MAPTRECQLKDM4EBLM | |
| SCHEMBL12473163 | 0.60 | MALT1 (0.62) | ALDH1A1MAPTRECQLKDM4EBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040492-A1 | METHODS OF TREATING CANCER COMPRISING TARGETING NQO1 | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-03-29 | — | — | WO | disclosed |