SCHEMBL1004526

SCHEMBL1004526

C1=CC2=NC=CC2=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2398119 0.71
SCHEMBL21630548 0.69
SCHEMBL2357161 0.65
SCHEMBL29103257 0.62
SCHEMBL26112668 0.62
SCHEMBL9578382 0.61
SCHEMBL26292 0.60
SCHEMBL1875110 0.59
SCHEMBL3150886 0.59
SCHEMBL8466052 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702615-A Supported metallocenes, catalysts containing same, their preparation and use 中国石油化工股份有限公司 2022-07-05 CN claimed
US-20150051179-A1 NOVEL STEROIDAL CYP17 INHIBITORS/ANTIANDROGENS TOKAI PHARMACEUTICALS, INC. 2015-02-19 US claimed
EP-1858879-B1 1,3-DIARYL SUBSTITUTED UREAS AS MODULATORS OF KINASE ACTIVITY GILEAD CONNECTICUT INC (US) 2012-06-06 EP claimed
US-20110312924-A1 NOVEL STEROIDAL CYP17 INHIBITORS/ANTIANDROGENS TOKAI PHARMACEUTICALS, INC. (US) 2011-12-22 US claimed
WO-2010091303-A1 NOVEL STEROIDAL CYP17 INHIBITORS/ANTIANDROGENS TOKAI PHARMACEUTICALS (US) 2010-08-12 WO claimed
EP-0680972-B1 Trifluoromethylketone peptide derivatives, process for their preparation and pharmaceutical compositions comprising them ADIR (FR) 2000-03-08 EP claimed
US-5567804-A HUMAN LEUCOCYTE ELASTASE INHIBITOR; ANTIOXIDANT ADIR ET COMPAGNIE (FR) 1996-10-22 US claimed
US-5565429-A HUMAN LEUCOCYTE ELASTASE INHIBITORS; EMPHYSEMA; ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES ADIR ET COMPAGNIE (FR) 1996-10-15 US claimed
EP-0680972-A1 Trifluoromethylketone peptide derivatives, process for their preparation and pharmaceutical compositions comprising them ADIR ET COMPAGNIE (FR) 1995-11-08 EP claimed
US-5190923-A For treatment of neurological disorders such as cognitive disorders ADIR ET COMPAGNIE (FR) 1993-03-02 US claimed
EP-0217688-B1 PEPTIDE DERIVATIVES WITH A LACTONIC OR CYCLOAMIDIC STRUCTURE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR ET COMPAGNIE (FR) 1990-09-26 EP claimed
US-4725581-A NERVOUS SYSTEM DISORDERS, COGNITION ACTIVATORS ADIR ET COMPAGNIE (FR) 1988-02-16 US claimed
US-4713459-A TRANSFERRING OXYGEN FOR HEMORRHAGE VICTIMS, PRESERVING ORGANS FOR SURGERY THE GREEN CROSS CORPORATION (JP) 1987-12-15 US claimed
EP-0217688-A1 Peptide derivatives with a lactonic or cycloamidic structure, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1987-04-08 EP claimed
EP-4199925-B1 CYCLOPENTAPYRROLE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-05-20 EP disclosed
US-12497362-B2 Cyclopentapyrrole orexin receptor agonists MERCK SHARP & DOHME LLC (US) 2025-12-16 US disclosed
US-12497362-B2 Cyclopentapyrrole orexin receptor agonists MERCK SHARP & DOHME LLC (US) 2025-12-16 US disclosed
EP-0299397-A2 Peptides with vasorelaxing, natriuretic and diuretic activities, preparation process, agents containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-18 EP disclosed
US-4725581-A NERVOUS SYSTEM DISORDERS, COGNITION ACTIVATORS ADIR ET COMPAGNIE (FR) 1988-02-16 US disclosed
EP-0231752-A2 Vasorelaxing, natriuretically and diuretically active peptides, process for their preparation, agents containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-12 EP disclosed