SCHEMBL10045595

SCHEMBL10045595

CCCCC1CCC(c2ccc(Cc3cc(N)cc(N)c3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 12/20 0.45
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
SPHK2 Q9NRA0 7/20 0.37
ESR2 Q92731 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12314554 0.96 SPHK1 (0.47) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL12731753 0.94 SPHK1 (0.48) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL13104834 0.94 SPHK1 (0.48) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL4322979 0.92 SPHK1 (0.44) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7752381 0.90 SPHK1 (0.48) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL12314552 0.88 CYP2C9 (0.49) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8164282 0.86 SPHK1 (0.50) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL2608100 0.85 SPHK1 (0.41) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7752525 0.85 SPHK1 (0.52) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7752570 0.85 SPHK1 (0.52) SPHK1CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530588-B2 Liquid crystal (LC) alignment agent, LC alignment film and LC display device having thereof CHI MEI CORPORATION (TW) 2013-09-10 US disclosed
US-8530588-B2 Liquid crystal (LC) alignment agent, LC alignment film and LC display device having thereof CHI MEI CORPORATION (TW) 2013-09-10 US disclosed
US-20120172542-A1 Liquid Crystal (LC) Alignment Agent, LC Alignment Film And LC Display Device Having Thereof CHI MEI CORPORATION (TW) 2012-07-05 US disclosed
US-20120172542-A1 Liquid Crystal (LC) Alignment Agent, LC Alignment Film And LC Display Device Having Thereof CHI MEI CORPORATION (TW) 2012-07-05 US disclosed
US-20120162588-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2012-06-28 US disclosed
US-20120162588-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2012-06-28 US disclosed