SCHEMBL1004669

SCHEMBL1004669

C=C(SC)SC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7500522 0.74 CYP1A2 (0.32)
SCHEMBL19018433 0.73
SCHEMBL22474802 0.71
SCHEMBL1454844 0.70
SCHEMBL677890 0.70
SCHEMBL775768 0.67
SCHEMBL13248600 0.67
SCHEMBL14303349 0.67
SCHEMBL13694516 0.67
SCHEMBL13028516 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189751-B2 Oxa(thia)zolidine compounds, process for preparation thereof and anti-inflammatory agents NIPPON SODA CO., LTD. (JP) 2007-03-13 US claimed
US-20040186096-A1 Oxa(thia)zolidine compounds, process for preparation thereof and anti-inflammatory agents NIPPON SODA CO., LTD. (JP) 2004-09-23 US claimed
EP-1410822-A1 OXA(THIA)ZOLIDINE COMPOUNDS, PROCESS FOR PREPARATION THEREOF AND ANTI-INFLAMMATORY AGENTS NIPPON SODA CO., LTD. (JP) 2004-04-21 EP claimed
WO-1998008387-A1 PLANT PROTECTANTS KHOMUTOV RADII M (RU) 1998-03-05 WO claimed
EP-0452729-B1 Process for preparing substituted cyclobutanes BRISTOL MYERS SQUIBB CO (US) 1995-07-12 EP claimed
US-5312963-A Process for preparing substituted cyclobutanes BRISTOL-MYERS SQUIBB CO. (US) 1994-05-17 US claimed
EP-0452729-A1 Process for preparing substituted cyclobutanes BRISTOL-MYERS SQUIBB COMPANY (US) 1991-10-23 EP claimed
EP-0092647-B1 NEW ACTIVE COMPOUNDS IN THE TREATMENT OF ULCERS AND SKIN ALLERGY SYMPTOMS MAGIS FARMACEUTICI S.p.A. (IT) 1987-01-14 EP claimed
JP-61246159-A None JP disclosed
US-20250276972-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) 2025-09-04 US disclosed
US-20240400577-A1 MODULATORS OF PROTEIN KINASES VIBLIOME THERAPEUTICS, LLC 2024-12-05 US disclosed
WO-2023183444-A1 MODULATORS OF PROTEIN KINASES VIBLIOME THERAPEUTICS, LLC (US) 2023-09-28 WO disclosed
WO-2022127756-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS Gritscience Biopharmaceuticals Co., Ltd. (CN) 2022-06-23 WO disclosed
US-9758509-B2 Substituted 3-(5-membered unsaturated heterocyclyl-1, 3-dihydro-indol-2-one's and derivatives thereof as kinase inhibitors ALLERGAN, INC. (US) 2017-09-12 US disclosed
EP-0516982-A1 Process for producing a heterocyclic tertiary amine NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-12-09 EP disclosed
EP-0452729-A1 Process for preparing substituted cyclobutanes BRISTOL-MYERS SQUIBB COMPANY (US) 1991-10-23 EP disclosed
WO-1990005730-A2 NOVEL CYCLOBUTANE DERIVATIVE AND PROCESS FOR PRODUCING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-05-31 WO disclosed
EP-0358154-A2 Novel cyclobutane derivative and process for producing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-03-14 EP disclosed
JP-S61246159-A ETHENE DERIVATIVE OOUCHI SHINKO KAGAKU KOGYO KK 1986-11-01 JP disclosed
EP-0010396-A1 Fungicidal and herbicidal compositions, certain cyanomethane and cyanoethene derivatives being active agents thereof, the preparation of these derivatives and methods for combating fungi and weeds FBC LIMITED (GB) 1980-04-30 EP disclosed