Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119466 | 0.83 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1127304 | 0.82 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL563195 | 0.82 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2074701 | 0.80 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2593140 | 0.79 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21832 | 0.79 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1224654 | 0.79 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL155563 | 0.78 | GAA (0.78) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL20706490 | 0.77 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4409901 | 0.77 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020742-A1 | NOVEL HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |
| US-7951965-B2 | Phenanthrene derivatives and organic light-emitting diodes containing said phenanthrene derivative | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-05-31 | — | — | US | disclosed |