Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297368 | 0.98 | ACE2 (0.50) | ACE2FAAHZDHHC7MAPTGPR84 | |
| Isobutane SCHEMBL29126862 | 0.98 | ACE2 (0.46) | ACE2FAAHCA1ZDHHC7MGAM | |
| SCHEMBL29248331 | 0.98 | ACE2 (0.50) | ACE2FAAHZDHHC7MAPTGPR84 | |
| SCHEMBL15756260 | 0.98 | ACE2 (0.50) | ACE2FAAHZDHHC7MAPTGPR84 | |
| Hydrochloric Acid SCHEMBL30110404 | 0.98 | ACE2 (0.46) | ACE2FAAHCA1ZDHHC7MGAM | |
| SCHEMBL28426484 | 0.98 | ACE2 (0.50) | ACE2FAAHZDHHC7MAPTGPR84 | |
| SCHEMBL28288920 | 0.98 | ACE2 (0.50) | ACE2FAAHZDHHC7MAPTGPR84 | |
| SCHEMBL6523473 | 0.98 | ACE2 (0.50) | ACE2FAAHZDHHC7MAPTGPR84 | |
| SCHEMBL12446351 | 0.98 | ACE2 (0.50) | ACE2FAAHZDHHC7MAPTGPR84 | |
| SCHEMBL1765985 | 0.94 | MGAM (0.43) | ACE2FAAHCA1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843295-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |
| WO-2014125121-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| EP-2739600-A1 | DIPHENYL SUBSTITUTED CYCLOHEXANE DERIVATIVES, USEFUL AS MODULATORS OF THE ESTROGEN RECEPTORS BETA | Acadia Pharmaceuticals Inc. (US) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013017619-A1 | DIPHENYL SUBSTITUTED CYCLOHEXANE DERIVATIVES, USEFUL AS MODULATORS OF THE ESTROGEN RECEPTORS BETA | ACADIA PHARMACEUTICALS INC. (US) | 2013-02-07 | — | — | WO | disclosed |
| WO-2012060387-A1 | NOVEL DIHYDROXYBENZENE DERIVATIVES AND ANTIPROTOZOAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | アリジェン製薬株式会社 (JP) | 2012-05-10 | — | — | WO | disclosed |